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Article

NOP3 is an essential yeast protein which is required for pre-rRNA processing.

The Journal of cell biology - 1 Nov 1992

Russell I D, Tollervey D

Abstract excerpt

The four nucleolar proteins NOP1, SSB1, GAR1, and NSR1 of Saccharomyces cerevisiae share a repetitive domain composed of repeat units rich in glycine and arginine (GAR domain). We have cloned and sequenced a fifth member of this family, NOP3, and shown it to be essential for cell viability. The NOP3 open reading frame encodes a 415 amino acid protein with a predicted molecular mass of 45 kD, containing a GAR...

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Source

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Identifiers

PMID: 1429834
DOI: 10.1083/jcb.119.4.737
PMCID: PMC2289684

Genes

GAL
GAR1
SDS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

NOP3 is an essential yeast protein which is required for pre-rRNA processing.PMID 1429834Read ↗

The yeast NOP4 gene product is an essential nucleolar protein required for pre-rRNA processing and accumulation of 60S ribosomal subunits.Semantic proximity Read ↗

Nucleolar protein Nop12p participates in synthesis of 25S rRNA in Saccharomyces cerevisiae.Semantic proximity Read ↗

Yeast Nop3p has structural and functional similarities to mammalian pre-mRNA binding proteins.Semantic proximity Read ↗

Nop53p, an essential nucleolar protein that interacts with Nop17p and Nip7p, is required for pre-rRNA processing in Saccharomyces cerevisiae.Semantic proximity Read ↗

Synthetic lethality with fibrillarin identifies NOP77p, a nucleolar protein required for pre-rRNA processing and modification.Semantic proximity Read ↗

Nop6, a component of 90S pre-ribosomal particles, is required for 40S ribosomal subunit biogenesis in Saccharomyces cerevisiae.Semantic proximity Read ↗

The yeast nucleolar protein Nop4p contains four RNA recognition motifs necessary for ribosome biogenesis.Semantic proximity Read ↗

Rrp8p is a yeast nucleolar protein functionally linked to Gar1p and involved in pre-rRNA cleavage at site A2.Semantic proximity Read ↗

Enp1, a yeast protein associated with U3 and U14 snoRNAs, is required for pre-rRNA processing and 40S subunit synthesis.Semantic proximity Read ↗

The Saccharomyces cerevisiae small GTPase, Gsp1p/Ran, is involved in 3' processing of 7S-to-5.8S rRNA and in degradation of the excised 5'-A0 fragment of 35S pre-rRNA, both of which are carried out by the exosome.Semantic proximity Read ↗

A small nucleolar RNP protein is required for pseudouridylation of eukaryotic ribosomal RNAs.Semantic proximity Read ↗

Rcl1p, the yeast protein similar to the RNA 3'-phosphate cyclase, associates with U3 snoRNP and is required for 18S rRNA biogenesis.Semantic proximity Read ↗

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