Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A suppressor of mutations in the region adjacent to iterons of pSC101 ori.

Journal of bacteriology - 1 Mar 1997

Ohkubo S, Yamaguchi K

Abstract excerpt

Some single-base changes in a 14-bp region (the downstream region) adjacent to three repeated sequences (iterons) in pSC101 ori are very deleterious for replication. We isolated a host suppressor mutation for one of these mutations and found that the suppressor suppressed all the mutations tested in the downstream region. The nucleotide sequence of the suppressor revealed that the suppressor gene was identical to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Proteins
Share to Base Sequence
Share to Escherichia coli

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, Bacterial

Share to Molecular Sequence Data

Share to Mutation

Share to Plasmids

Share to Repetitive Sequences, Nucleic Acid

Source

Open in PubMed Open full text

Identifiers

PMID: 9068662
DOI: 10.1128/jb.179.6.2089-2091.1997
PMCID: PMC178940

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A suppressor of mutations in the region adjacent to iterons of pSC101 ori.PMID 9068662Read ↗

Novel alleles of the Escherichia coli dnaA gene are defective in replication of pSC101 but not of oriC.Semantic proximity Read ↗

An essential iteron-binding protein required for plasmid R1162 replication induces localized melting within the origin at a specific site in AT-rich DNA.Semantic proximity Read ↗

Variation in the replication loci of Streptomyces linear plasmids.Semantic proximity Read ↗

Novel alleles of the Escherichia coli dnaA gene.Semantic proximity Read ↗

Destabilized inheritance of pSC101 and other Escherichia coli plasmids by DpiA, a novel two-component system regulator.Semantic proximity Read ↗

A mutation of the transactivation gene of satellite bacteriophage P4 that suppresses the rpoA109 mutation of Escherichia coli.Semantic proximity Read ↗

Replication origin mutations affecting binding of pSC101 plasmid-encoded Rep initiator protein.Semantic proximity Read ↗

The replication origin of pSC101: the nucleotide sequence and replication functions of the ori region.Semantic proximity Read ↗

Binding modes of the initiator and inhibitor forms of the replication protein pi to the gamma ori iteron of plasmid R6K.Semantic proximity Read ↗

Suppressors of the temperature sensitivity of DNA polymerase alpha mutations in Saccharomyces cerevisiae.Semantic proximity Read ↗

Replication initiation at a distance: determination of the cis- and trans-acting elements of replication origin alpha of plasmid R6K.Semantic proximity Read ↗

Mechanism of origin activation by monomers of R6K-encoded pi protein.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.