A suppressor of mutations in the region adjacent to iterons of pSC101 ori.

doi:10.1128/jb.179.6.2089-2091.1997

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Article

A suppressor of mutations in the region adjacent to iterons of pSC101 ori.

Journal of bacteriology - 1 Mar 1997

Ohkubo S, Yamaguchi K

Abstract excerpt

Some single-base changes in a 14-bp region (the downstream region) adjacent to three repeated sequences (iterons) in pSC101 ori are very deleterious for replication. We isolated a host suppressor mutation for one of these mutations and found that the suppressor suppressed all the mutations tested in the downstream region. The nucleotide sequence of the suppressor revealed that the suppressor gene was identical to...

Topics

Bacterial Proteins
Base Sequence
DNA Replication
Escherichia coli
Escherichia coli Proteins
Genes, Bacterial
Genes, Suppressor
Molecular Sequence Data
Mutation
Plasmids
Repetitive Sequences, Nucleic Acid
Replication Origin
Suppression, Genetic
Transformation, Bacterial

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Identifiers

PMID: 9068662
DOI: 10.1128/jb.179.6.2089-2091.1997
PMCID: PMC178940

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