Article
The neurogenic suppressor of hairless DNA-binding protein mediates the transcriptional activation of the enhancer of split complex genes triggered by Notch signaling.
Genes & development - 1 Nov 1995
Lecourtois M, Schweisguth F
Abstract excerpt
The Notch protein (N) acts as a transmembrane receptor for intercellular signals controlling cell fate choices in vertebrates and invertebrates. The signal of N activation may be transduced directly from the cell surface into the nucleus by an evolutionarily conserved transcription factor, Suppre...
Topics
- Animals
- Base Sequence
- Basic Helix-Loop-Helix Transcription Factors
- Binding Sites
- DNA-Binding Proteins
- Drosophila
- Drosophila Proteins
- Ectoderm
- Embryo, Nonmammalian
- Embryonic Induction
- Enhancer Elements, Genetic
- Gene Expression Regulation, Developmental
- Genes, Suppressor
- Helix-Loop-Helix Motifs
- Homozygote
- Membrane Proteins
- Molecular Sequence Data
- Mutation