Article
Zebrafish Her8a is activated by Su(H)-dependent Notch signaling and is essential for the inhibition of neurogenesis.
PloS one - 26 Apr 2011
Chung Pei-Chen, Lin Wen-Shiuan, Scotting Paul J, Hsieh Fu-Yu, Wu Hui-Lan, Cheng Yi-Chuan
Abstract excerpt
Understanding how diversity of neural cells is generated is one of the main tasks of developmental biology. The Hairy/E(spl) family members are potential targets of Notch signaling, which has been shown to be fundamental to neural cell maintenance, cell fate decisions, and compartment boundary formation. However, their response to Notch signaling and their roles in neurogenesis are still not fully understood. In...
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