Article
Developmental regulation of genomic imprinting during gametogenesis.
Developmental biology - 1 Nov 1995
Villar A J, Eddy E M, Pedersen R A
Abstract excerpt
Successful mammalian development requires both the male and female genomes. This is due in part to genomic imprinting, which results in offspring inheriting only one functional copy of a gene from either the mother or the father. Evidence suggests that this specialization of the parental genomes is established during gametogenesis when the imprint pattern inherited from the parent is switched to reflect the sex...
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