Article
Epigenotype switching of imprintable loci in embryonic germ cells.
Development genes and evolution - 1 Feb 1998
Tada T, Tada M, Hilton K, Barton S C, Sado T, Takagi N, Surani M A
Abstract excerpt
Expression of imprinted genes is dependent on their parental origin. This is reflected in the heritable differential methylation of parental alleles. The gametic imprints are however reversible as they do not endure for more than one generation. To investigate if the epigenetic changes in male and female germ line are similar or not, we derived embryonic germ (EG) cells from primordial germ cells (PGCs) of day...
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