Potential significance of genomic imprinting defects for reproduction and assisted reproductive technology

Abstract excerpt

Recent studies suggest a possible link between human assisted reproductive technology and genomic imprinting disorders. Assisted reproductive technology includes the isolation, handling and culture of gametes and early embryos at times when imprinted genes are likely to be particularly vulnerable to external influences. Evidence of sex-specific differences in imprint acquisition suggests that male and female germ...

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• Share to Epigenetics and DNA Methylation
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