Article
Epigenetic modification and imprinting of the mammalian genome during development.
Current topics in developmental biology - 1 Jan 1999
Latham K E
Abstract excerpt
Genomic imprinting in mammals results in the differential expression of maternal and paternal alleles of certain genes. Recent observations have revealed that the regulation of imprinted genes is only partially determined by epigenetic modifications imposed on the two parental genomes during gametogenesis. Additional modifications mediated by factors in the ooplasm, early embryo, or developing embryonic tissues...
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