Article
Igf2r and Igf2 gene expression in androgenetic, gynogenetic, and parthenogenetic preimplantation mouse embryos: absence of regulation by genomic imprinting.
Genes & development - 1 Feb 1994
Latham K E, Doherty A S, Scott C D, Schultz R M
Abstract excerpt
Genomic imprinting in mammals is believed to result from modifications to chromosomes during gametogenesis that inactivate the paternal or maternal allele. The genes encoding the insulin-like growth factor type 2 (Igf2) and its receptor (Igf2r) are reciprocally imprinted and expressed from the pa...
Topics
- Alleles
- Animals
- Blastocyst
- Cleavage Stage, Ovum
- Embryonic and Fetal Development
- Fathers
- Female
- Gene Expression Regulation
- Gestational Age
- Insulin-Like Growth Factor II
- Male
- Methylation
- Mice
- Morula
- Mothers
- Parthenogenesis
- Polymerase Chain Reaction
- RNA, Messenger