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Article

Early transcription from the maternal genome controlling blastomere integrity in mouse two-cell-stage embryos.

American journal of physiology. Cell physiology - 1 May 2010

Han Zhiming, Mtango Namdori R, Zhong Zhisheng, Vassena Rita, Latham Keith E

Abstract excerpt

Blastomere cytofragmentation in mammalian embryos poses a significant problem in applied and clinical embryology. Mouse two-cell-stage embryos display strain-dependent differences in the rate of cytofragmentation, with a high rate observed in C3H/HeJ embryos and a lower rate observed in C57BL/6 embryos. The maternally inherited genome exerts the strongest effect on the process, with lesser effects mediated by the...

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Source

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Identifiers

PMID: 20107036
DOI: 10.1152/ajpcell.00393.2009
PMCID: PMC2867389

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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