Article
Lack of elevated drug efflux in adriamycin-resistant immunoblastic B lymphoma cells with mdr1 overexpression.
FEBS letters - 16 Oct 1995
Chao C C
Abstract excerpt
A multidrug-resistant (MDR) subline of the immunoblastic B lymphoma cell line was established by sequentially selecting in increasing concentrations of adriamycin. The adriamycin-resistant cell line (HOB1/ADR) demonstrated resistance to a wide spectrum of chemotherapeutic agents including MDR dru...
Topics
- ATP Binding Cassette Transporter, Subfamily B, Member 1
- Antineoplastic Agents
- Base Sequence
- Blotting, Western
- Cell Division
- Doxorubicin
- Drug Resistance, Multiple
- Drug Resistance, Neoplasm
- Gene Dosage
- Gene Expression
- Humans
- Lymphoma, B-Cell
- Molecular Sequence Data
- Phenotype
- Polymerase Chain Reaction
- Precursor Cell Lymphoblastic Leukemia-Lymphoma
- RNA, Messenger
- Tumor Cells, Cultured
