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Article

Intrinsic resistance to chemotherapeutic agents in murine osteosarcoma cells.

The Journal of bone and joint surgery. American volume - 1 Jul 2000

Takeshita H, Kusuzaki K, Ashihara T, Gebhardt M C, Mankin H J, Hirasawa Y

Abstract excerpt

BACKGROUND: There are two general categories of drug resistance: acquired and intrinsic. The mechanisms involved in acquired drug resistance have been extensively studied, and several mechanisms have been described. However, the mechanisms responsible for intrinsic drug resistance have not been elucidated, to our knowledge. The purpose of the present study was to investigate the cytological and biochemical...

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PMID: 10901311
DOI: 10.2106/00004623-200007000-00008

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MOS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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