Article
A human B-cell lymphoma line with a de novo multidrug resistance phenotype.
Cancer - 15 Mar 1992
Mohammad R M, Mohamed A N, KuKuruga M, Smith M R, al-Katib A
Abstract excerpt
A human diffuse large cell lymphoma line (WSU-DLCL) expressing multidrug resistance (MDR) was established from a patient with primary chemotherapy-resistant disease. This cell line has the same phenotypic features as malignant cells from the patient. The established cell line has features of a ma...
Topics
- Adult
- Antineoplastic Agents
- Cell Line
- Chromosome Aberrations
- Chromosome Disorders
- Chromosomes, Human, Pair 8
- Drug Resistance
- Female
- Gene Expression
- Gene Rearrangement, B-Lymphocyte
- Head and Neck Neoplasms
- Humans
- Immunoglobulin M
- Immunoglobulin kappa-Chains
- Immunophenotyping
- Lymphoma, B-Cell
- Lymphoma, Large B-Cell, Diffuse
- Phenotype