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Article

Identification and characterization of a neuroendocrine-specific 5'-regulatory region of the human chromogranin A gene.

Endocrinology - 1 Dec 1995

Nolan E M, Cheung T C, Burton D W, Deftos L J

Abstract excerpt

Chromogranin A (CgA) expression is specific to cells of endocrine and neuroendocrine (NE) tissues. Our transfection studies with CgA have identified two DNA regions 5' of the transcription start site that regulate CgA gene transcription: a distal regulatory region (DRR) located between -726 and -455, and a proximal regulatory region (PRR) between -60 and -26. In studies of the DRR using four human NE and six...

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PMID: 7588318
DOI: 10.1210/endo.136.12.7588318

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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