Article
Neuroendocrine cell type-specific and inducible expression of the secretogranin II gene: crucial role of cyclic adenosine monophosphate and serum response elements.
Endocrinology - 1 Feb 1999
Mahata S K, Mahata M, Livsey C V, Gerdes H H, Huttner W B, O'Connor D T
Abstract excerpt
Secretogranin II, an acidic protein in the chromogranin/secretogranin family, is widely distributed in neuroendocrine secretory granules. What factors govern such widespread, yet selective, expression? The 5' deletions localized neuroendocrine cell type-specific expression to the proximal mouse secretogranin II promoter: such expression was abolished after deletion past the cAMP response element (CRE; [-67...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.