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Article

Characterization of promoter elements regulating the expression of the human neurotensin/neuromedin N gene.

The Journal of biological chemistry - 7 Jan 2011

Wang Xiaofu, Gulhati Pat, Li Jing, Dobner Paul R, Weiss Heidi, Townsend Courtney M, Evers B Mark

Abstract excerpt

Expression of the gene encoding neurotensin/neuromedin N (NT/N) is mostly limited to the brain and specialized enteroendocrine N cells in the distal small intestine. We have identified key regulatory elements in the promoter region that are involved in human NT/N (hNT/N) gene expression in the novel human endocrine cell line, BON, which resembles intestinal N cells in several important aspects including NT/N...

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Identifiers

PMID: 21030593
DOI: 10.1074/jbc.M110.145664
PMCID: PMC3013014

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