Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Roles of insulin-like growth factor (IGF) receptors and IGF-binding proteins in IGF-II-induced proliferation and differentiation of L6A1 rat myoblasts.

Endocrinology - 1 Nov 1995

Bach L A, Salemi R, Leeding K S

Abstract excerpt

Insulin-like growth factor II (IGF-II) stimulates the proliferation and differentiation of rat myoblasts. Previous studies suggest that these response are mediated by the IGF-I receptor, but the IGF-II/mannose 6-phosphate receptor was recently implicated in differentiation of mouse myoblasts. L6A...

Topics

Animals
Azo Compounds
Cell Differentiation
Cell Division
Cell Line
Coloring Agents
Insulin-Like Growth Factor Binding Protein 6
Insulin-Like Growth Factor Binding Proteins
Insulin-Like Growth Factor II
Muscles
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Rats

Receptor, IGF Type 1

Receptor, IGF Type 2

Receptors, Somatomedin

Recombinant Proteins

Source

Identifiers

PMID: 7588242
DOI: 10.1210/endo.136.11.7588242

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7588242-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Roles of insulin-like growth factor (IGF) receptors and IGF-binding proteins in IGF-II-induced proliferation and differentiation of L6A1 rat myoblasts.PMID 7588242Read ↗

IGF‐II is more active than IGF‐I in stimulating L6A1 myogenesis: Greater mitogenic actions of IGF‐I delay differentiationSemantic proximity Read ↗

Insulin-like growth factor-binding protein-6 and cancerSemantic proximity Read ↗

Promotion of cancer cell migration: an insulin-like growth factor (IGF)-independent action of IGF-binding protein-6.Semantic proximity Read ↗

Porcine IGF-1R synonymous mutations in the intracellular domain affect cell proliferation and alter kinase activity.Semantic proximity Read ↗

Role of Insulin-Like Growth Factor Receptor 2 across Muscle Homeostasis: Implications for Treating Muscular DystrophySemantic proximity Read ↗

Minireview: Mechano-Growth Factor: A Putative Product of IGF-I Gene Expression Involved in Tissue Repair and RegenerationSemantic proximity Read ↗

Comparative effects of insulin-like growth factor II (IGF-II) and IGF-II mutants specific for IGF-II/CIM6-P or IGF-I receptors on in vitro hematopoiesis.Semantic proximity Read ↗

Insulin-like growth factor binding protein-5 modulates muscle differentiation through an insulin-like growth factor-dependent mechanism.Semantic proximity Read ↗

Differential expression of IGF system components in proliferating vs. differentiating growth plate chondrocytes: the functional role of IGFBP-5Semantic proximity Read ↗

Rabbit slow and fast skeletal muscle-derived satellite myoblast phenotypes do not involve constitutive differences in the components of the insulin-like growth factor system.Semantic proximity Read ↗

Interleukin-6 Induces Myogenic Differentiation via JAK2-STAT3 Signaling in Mouse C2C12 Myoblast Cell Line and Primary Human MyoblastsSemantic proximity Read ↗

Insulin-like growth factor-2/mannose-6 phosphate receptors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.