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Article

Differential expression of IGF system components in proliferating vs. differentiating growth plate chondrocytes: the functional role of IGFBP-5

4 Oct 2005

Abstract excerpt

The growth plate is an important target tissue for insulin-like growth factors (IGFs), but little is known about the regulation of the IGF system during the developmental sequence of chondrocytes. We therefore examined the expression profile of IGF system components in proliferating vs. differentiating growth plate chondrocytes by use of two cell culture models of the growth cartilage. In rat growth plate...

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PMID: 16204335
DOI: 10.1152/ajpendo.00363.2005

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Source receipt: pubmed, retrieved 7 Sept 2026.

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