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Article

IGF‐II is more active than IGF‐I in stimulating L6A1 myogenesis: Greater mitogenic actions of IGF‐I delay differentiation

1 Nov 1994

Abstract excerpt

Mitogens are generally thought to inhibit myogenesis, and many cell biologists have found it hard to interpret observations that the insulin-like growth factors (IGFs) stimulate both proliferation and differentiation of muscle cells in culture. Our previous studies suggested that the Type I IGF receptor mediates these actions. However, IGF-II and insulin treatment caused myoblasts to differentiate much more...

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Share to Growth Hormone and Insulin-like Growth Factors
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PMID: 7962112
DOI: 10.1002/jcp.1041610212

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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IGF‐II is more active than IGF‐I in stimulating L6A1 myogenesis: Greater mitogenic actions of IGF‐I delay differentiationPMID 7962112Read ↗

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