Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Minireview: Mechano-Growth Factor: A Putative Product of IGF-I Gene Expression Involved in Tissue Repair and Regeneration

3 Feb 2010

Abstract excerpt

The discovery that IGF-I mRNAs encoding isoforms of the pro-IGF-I molecule are differentially regulated in response to mechanical stress in skeletal muscle has been the impetus for a number of studies designed to demonstrate that alternative splicing of IGF-I pre-mRNA involving exons 4, 5, and 6 gives rise to a unique peptide derived from pro-IGF-I that plays a novel role in myoblast proliferation. Research...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic Neurodegenerative Diseases
Share to Muscle Physiology and Disorders
Share to Neurogenetic and Muscular Disorders Research

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20130113
DOI: 10.1210/en.2009-1217

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 19 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Minireview: Mechano-Growth Factor: A Putative Product of IGF-I Gene Expression Involved in Tissue Repair and RegenerationPMID 20130113Read ↗

Mechano Growth Factor E peptide (MGF-E), derived from an isoform of IGF-1, activates human muscle progenitor cells and induces an increase in their fusion potential at different agesSemantic proximity Read ↗

Role of Alternatively Spliced Messenger RNA (mRNA) Isoforms of the Insulin-Like Growth Factor 1 (IGF1) in Selected Human TumorsSemantic proximity Read ↗

Mechanical Signals, IGF-I Gene Splicing, and Muscle AdaptationSemantic proximity Read ↗

Expression of IGF-I splice variants in young and old human skeletal muscle after high resistance exerciseSemantic proximity Read ↗

Expression of IGF-I splice variants in young and old human skeletal muscle after high resistance exerciseSemantic proximity Read ↗

40 YEARS OF IGF1: Insulin-like growth factors: actions on the skeletonSemantic proximity Read ↗

CRISPR‐Cas9–induced IGF1 gene activation as a tool for enhancing muscle differentiation via multiple isoform expressionSemantic proximity Read ↗

Insulin‐like growth factor‐I E peptides: implications for ageing skeletal muscleSemantic proximity Read ↗

Muscle mechano growth factor is preferentially induced by growth hormone in growth hormone-deficient lit/lit mice.Semantic proximity Read ↗

IGF-1 regulation of key signaling pathways in boneSemantic proximity Read ↗

The Insulin-like Growth Factor Signalling Pathway in Cardiac Development and RegenerationSemantic proximity Read ↗

Magic-factor 1, a partial agonist of Met, induces muscle hypertrophy by protecting myogenic progenitors from apoptosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.