Article
Insulin-like growth factor-2/mannose-6 phosphate receptors.
Vitamins and hormones - 1 Jan 2009
El-Shewy Hesham M, Luttrell Louis M
Abstract excerpt
The insulin-like growth factor type 2/mannose-6-phosphate (IGF-2/M6P) receptor is a multifunctional single transmembrane glycoprotein that is known to regulate diverse biological functions. It is composed of a large extracytoplasmic domain, a single transmembrane region and a short cytoplasmic tail that lacks intrinsic catalytic activity. The receptor cycles continuously between intracellular compartments and the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
