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Article

Functional circularity of legitimate Qbeta replicase templates.

Journal of molecular biology - 6 Jun 2008

Ugarov Victor I, Chetverin Alexander B

Abstract excerpt

Qbeta replicase (RNA-directed RNA polymerase of bacteriophage Qbeta) exponentially amplifies certain RNAs in vitro. Previous studies have shown that Qbeta replicase can initiate and elongate on a variety of RNAs; however, only a minute fraction of them are recognized as 'legitimate' templates. Guanosine 5'-triphosphate (GTP)-dependent initiation on a legitimate template generates a stable replicative complex...

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Identifiers

PMID: 18466922
DOI: 10.1016/j.jmb.2008.03.074
PMCID: PMC7173182

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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