Stability of replicative form and fitness among RNA variants transcribed by Qbeta replicase.

doi:10.1098/rspb.1995.0056

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Article

Stability of replicative form and fitness among RNA variants transcribed by Qbeta replicase.

Proceedings. Biological sciences - 22 Apr 1995

Davis B K

Abstract excerpt

Stability in the replicative form of RNA molecules transcribed by Qbeta replicase was demonstrated to provide a sequence-dependent indicator of their fitness. This follows from the finding that replication rates reported for 17 RNA species (genome length, 77-370 nucleotides) correlate with the se...

Topics

Allolevivirus
Genetic Variation
Models, Chemical
Q beta Replicase
RNA, Viral
Templates, Genetic
Thermodynamics
Transcription, Genetic
Virus Replication

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