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Article

Polymorphisms of the D4 dopamine receptor alleles in chronic alcoholism.

Biochemical and biophysical research communications - 15 Oct 1993

George S R, Cheng R, Nguyen T, Israel Y, O'Dowd B F

Abstract excerpt

We have screened genomic DNA for the identification of D4 dopamine receptor polymorphisms. We show that the D4 dopamine receptor genotype in 72 severely affected chronic alcoholics is heterogeneous, with individuals homozygous and heterozygous for the various D4 receptor alleles. Alcoholics demon...

Topics

Adult
Alcoholism
Alleles
Amino Acid Sequence
Base Sequence
Female
Genotype
Heterozygote
Homozygote
Humans
Male
Molecular Sequence Data
Multigene Family

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Genetic

Receptors, Dopamine

Receptors, Dopamine D2

Receptors, Dopamine D4

Smoking

Source

Identifiers

PMID: 8216280
DOI: 10.1006/bbrc.1993.2222

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8216280-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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