Article
D2 dopamine receptor genotype and cerebrospinal fluid homovanillic acid, 5-hydroxyindoleacetic acid and 3-methoxy-4-hydroxyphenylglycol in alcoholics in Finland and the United States.
Acta psychiatrica Scandinavica - 1 Nov 1992
Goldman D, Dean M, Brown G L, Bolos A M, Tokola R, Virkkunen M, Linnoila M
Abstract excerpt
If a genetic association between the D2 dopamine receptor genotype and alcoholism is mediated by altered dopamine function, then a stronger association might be found in alcoholics who are deviant in indices of dopamine function and by comparing alcoholics to nonalcoholics matched for ethnic origin. Therefore, we evaluated the D2/TaqI polymorphism in 29 impulsive violent alcoholic Finns, 17 nonimpulsive violent...
Topics
- Adult
- Alcoholism
- Alleles
- Ethnicity
- Finland
- Genotype
- Homovanillic Acid
- Humans
- Hydroxyindoleacetic Acid
- Male
- Methoxyhydroxyphenylglycol