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Article

TNF-alpha gene polymorphism: clinical and biological implications.

Microscopy research and technique - 1 Aug 2000

Hajeer A H, Hutchinson I V

Abstract excerpt

TNF-alpha is a proinflammatory cytokine that has been implicated in the severity of different immune-regulated diseases including autoimmune diseases and transplantation. The gene for TNF-alpha is located within the MHC region on chromosome 6p21.3. This is a highly polymorphic region, and the TNF-alpha itself contains a large number of polymorphisms. Some of these polymorphisms form extended haplotypes with the...

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Identifiers

PMID: 10891887
DOI: 10.1002/1097-0029(20000801)50:3<216::AID-JEMT5>3.0.CO;2-Q

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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