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Article

Somatic mutations in the brain: relationship to aging?

Mutation research - 1 Oct 1995

Evans D A, Burbach J P, van Leeuwen F W

Abstract excerpt

Genetic instability is generally thought to underlie the process of aging and is predominantly associated with meiosis and mitosis. This review will discuss DNA damage and repair, somatic mutations and somatic recombination events in non-dividing neurons in relation to aging. In general it can be concluded that mutagenesis operates at high frequency in the brain. Present data do not provide clear evidence for...

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PMID: 7565872
DOI: 10.1016/0921-8734(95)00022-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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