From DNA damage to mutations: All roads lead to aging.

Abstract excerpt

Damage to the repository of genetic information in cells has plagued life since its very beginning 3-4 billion years ago. Initially, in the absence of an ozone layer, especially damage from solar UV radiation must have been frequent, with other sources, most notably endogenous sources related to cell metabolism, gaining in importance over time. To cope with this high frequency of damage to the increasingly long...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Aging
• Share to DNA Damage
• Share to DNA Repair