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Article

Molecular misreading in non-neuronal cells.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Aug 2000

Van Leeuwen F W, Hol E M, Hermanussen R W, Sonnemans M A, Moraal E, Fischer D F, Evans D A, Chooi K F, Burbach J P, Murphy D

Abstract excerpt

+1 Frame-shifted proteins such as amyloid precursor protein(+1) and ubiquitin-B(+1) have been identified in the neuropathological hallmarks of Alzheimer's disease. These frameshifts are caused by dinucleotide deletions in GAGAG motifs of messenger RNA encoded by genes that have maintained the unchanged wild-type DNA sequence. This process is termed 'molecular misreading'. A key question is whether this process is...

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Identifiers

PMID: 10928994
DOI: 10.1096/fj.14.11.1595

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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