Article
Somatic mutations in neurons during aging and neurodegeneration.
Acta neuropathologica - 1 Jun 2018
Verheijen Bert M, Vermulst Marc, van Leeuwen Fred W
Abstract excerpt
The nervous system is composed of a large variety of neurons with a diverse array of morphological and functional properties. This heterogeneity is essential for the construction and maintenance of a distinct set of neural networks with unique characteristics. Accumulating evidence now indicates that neurons do not only differ at a functional level, but also at the genomic level. These genomic discrepancies seem...
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