Article
Transcriptional regulation of the chicken caldesmon gene. Activation of gizzard-type caldesmon promoter requires a CArG box-like motif.
The Journal of biological chemistry - 6 Oct 1995
Yano H, Hayashi K, Momiyama T, Saga H, Haruna M, Sobue K
Abstract excerpt
Caldesmon, which plays a vital role in the actomyosin system, is distributed in smooth muscle and non-muscle cells, and its isoformal interconversion between a high M(r) form and low M(r) form is a favorable molecular event for studying phenotypic modulation of smooth muscle cells. Genomic analysis reveals two promoters, of which the gizzard-type promoter displays much higher activity than the brain-type...
Topics
- Animals
- Base Sequence
- Calmodulin-Binding Proteins
- Cell Line
- Chick Embryo
- Chickens
- Culture Media
- DNA
- DNA Probes
- DNA-Binding Proteins
- Gene Expression Regulation