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Article

HLA-DQ genetics in children with celiac disease: a meta-analysis suggesting a two-step genetic screening procedure starting with HLA-DQ β chains.

Pediatric research - 1 Mar 2018

De Silvestri Annalisa, Capittini Cristina, Poddighe Dimitri, Valsecchi Chiara, Marseglia Gianluigi, Tagliacarne Sara Carlotta, Scotti Valeria, Rebuffi Chiara, Pasi Annamaria, Martinetti Miryam, Tinelli Carmine

Abstract excerpt

BackgroundSpecific HLA-DQ genes have been recognized as necessary - but not sufficient - factors for the occurrence of Celiac Disease (CD). Through a meta-analysis, evaluating the distribution of CD-related HLA genotypes in children, we aimed at providing insights for a potential widened screening strategy.MethodsAfter a systematic search on the association between class II HLA genes and CD in children, 46...

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PMID: 29244800
DOI: 10.1038/pr.2017.307

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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