Article
Genetic polymorphisms of cytochrome p450 2E1, glutathione S-transferase M1 and T1, and susceptibility to gastric carcinoma in Taiwan.
International journal of colorectal disease - 1 Sept 2002
Wu Ming-Shiang, Chen Chien-Jen, Lin Ming-Tsan, Wang Hsiu-Po, Shun Chia-Tung, Sheu Jin-Chuan, Lin Jaw-Town
Abstract excerpt
BACKGROUND AND AIMS: Cytochrome p450 (CYP) and glutathione S-transferase (GST) enzymes are involved in activation and detoxification of many potential carcinogens. Genetic polymorphisms in these enzymes have been found to influence interindividual and interethnic susceptibility to cancer. Although CYP and GST enzymes are involved in the activation and detoxification of N-nitrosamines and related compound, studies...
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