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Article

CYP enzyme polymorphisms and susceptibility to HCV-related chronic liver disease and liver cancer.

International journal of cancer - 10 Apr 2003

Silvestri Laura, Sonzogni Laura, De Silvestri Annalisa, Gritti Chiara, Foti Luciana, Zavaglia Claudio, Leveri Michela, Cividini Agostino, Mondelli Mario U, Civardi Emilio, Silini Enrico M

Abstract excerpt

Cancer risk can be influenced by the exposure to endogenous or environmental toxins. Polymorphic enzymes involved in the metabolic activation/detoxification of carcinogens may account for individual variations of risk. We studied the polymorphisms of five enzymes of the P450 superfamily, CYP1A1, CYP1A2, CYP2D6, CYP2E1 and CY3A4, as risk factors for liver disease progression and cancer in hepatitis C...

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Identifiers

PMID: 12569554
DOI: 10.1002/ijc.10937

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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