Effects of the umuDC, mucAB, and samAB operons on the mutational specificity of chemical mutagenesis in Escherichia coli: I. Frameshift mutagenesis.

doi:10.1016/0921-8777(94)90058-2

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Article

Effects of the umuDC, mucAB, and samAB operons on the mutational specificity of chemical mutagenesis in Escherichia coli: I. Frameshift mutagenesis.

Mutation research - 1 Jan 1994

Watanabe M, Nohmi T, Ohta T

Abstract excerpt

The specificity of frameshift mutations induced by several classes of chemical mutagens was determined using a collection of mutant E. coli lacZ genes. This collection can detect each of five kinds of specific frameshift events by scoring Lac+ revertant colonies. In addition, the mutational spectra were characterized in backgrounds carrying plasmids that encode the umuDC, mucAB, or samAB operon. 4-Nitroquinoline...

Topics

4-Nitroquinoline-1-oxide
Alleles
Aminacrine
DNA Mutational Analysis
DNA, Bacterial
Escherichia coli
Frameshift Mutation
Furylfuramide
Lac Operon
Methylnitronitrosoguanidine
Mitomycin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutagenesis, Site-Directed

Mutagens

Nitrogen Mustard Compounds

Operon

Plasmids

SOS Response, Genetics

Suppression, Genetic

Source

Open in PubMed

Identifiers

PMID: 7504189
DOI: 10.1016/0921-8777(94)90058-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7504189-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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