Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The C. elegans gene lin-44, which controls the polarity of certain asymmetric cell divisions, encodes a Wnt protein and acts cell nonautonomously.

Cell - 6 Oct 1995

Herman M A, Vassilieva L L, Horvitz H R, Shaw J E, Herman R K

Abstract excerpt

Mutations in the C. elegans gene lin-44 lead to reversals in the polarity of certain asymmetric cell divisions. We have discovered that lin-44 is a member of the Wnt family of genes, which encode secretory glycoproteins implicated in intercellular signaling. Both in situ hybridization experiments using lin-44 transcripts and experiments using reporter constructs designed to mimic patterns of lin-44 expression...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Base Sequence

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cell Division

Share to DNA, Complementary

Share to Drosophila melanogaster

Share to Drosophila Proteins

Share to Gene Expression Regulation

Share to Glycoproteins

Source

Identifiers

PMID: 7553861
DOI: 10.1016/0092-8674(95)90238-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The C. elegans gene lin-44, which controls the polarity of certain asymmetric cell divisions, encodes a Wnt protein and acts cell nonautonomously.PMID 7553861Read ↗

The Caenorhabditis elegans gene lin-44 controls the polarity of asymmetric cell divisions.Semantic proximity Read ↗

The Caenorhabditis elegans gene lin-17, which is required for certain asymmetric cell divisions, encodes a putative seven-transmembrane protein similar to the Drosophila frizzled protein.Semantic proximity Read ↗

Wnt signals and frizzled activity orient anterior-posterior axon outgrowth in C. elegans.Semantic proximity Read ↗

LIN-44/Wnt directs dendrite outgrowth through LIN-17/Frizzled in C. elegans Neurons.Semantic proximity Read ↗

Multiple levels of regulation specify the polarity of an asymmetric cell division in C. elegans.Semantic proximity Read ↗

Distinct functions of three Wnt proteins control mirror-symmetric organogenesis in the C. elegans gonad.Semantic proximity Read ↗

Wnt signaling polarizes an early C. elegans blastomere to distinguish endoderm from mesoderm.Semantic proximity Read ↗

Cell shape and Wnt signaling redundantly control the division axis of C. elegans epithelial stem cells.Semantic proximity Read ↗

Wnt signaling controls the stem cell-like asymmetric division of the epithelial seam cells during C. elegans larval developmentSemantic proximity Read ↗

Wnt signaling establishes anteroposterior neuronal polarity and requires retromer in C. elegans.Semantic proximity Read ↗

C. elegans POP-1/TCF functions in a canonical Wnt pathway that controls cell migration and in a noncanonical Wnt pathway that controls cell polarity.Semantic proximity Read ↗

Multiple Wnts Redundantly Control Polarity Orientation in Caenorhabditis elegans Epithelial Stem CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.