Article
Multiple levels of regulation specify the polarity of an asymmetric cell division in C. elegans.
Development (Cambridge, England) - 1 Nov 2000
Whangbo J, Harris J, Kenyon C
Abstract excerpt
Wnt signaling systems play important roles in the generation of cell and tissue polarity during development. We describe a Wnt signaling system that acts in a new way to orient the polarity of an epidermal cell division in C. elegans. In this system, the EGL-20/Wnt signal acts in a permissive fashion to polarize the asymmetric division of a cell called V5. EGL-20 regulates this polarization by counteracting...
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