Article
Distinct functions of three Wnt proteins control mirror-symmetric organogenesis in the C. elegans gonad.
eLife - 1 Nov 2024
So Shuhei, Asakawa Masayo, Sawa Hitoshi
Abstract excerpt
Organogenesis requires the proper production of diverse cell types and their positioning/migration. However, the coordination of these processes during development remains poorly understood. The gonad in C. elegans exhibits a mirror-symmetric structure guided by the migration of distal tip cells (DTCs), which result from asymmetric divisions of somatic gonadal precursors (SGPs; Z1 and Z4). We found that the...
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