Article
The Caenorhabditis elegans gene lin-44 controls the polarity of asymmetric cell divisions.
Development (Cambridge, England) - 1 May 1994
Herman M A, Horvitz H R
Abstract excerpt
The generation and orientation of cellular and organismic polarity are fundamental aspects of development. Mutations in the gene lin-44 of the nematode Caenorhabditis elegans reverse both the relative positions of specific sister cells and the apparent polarities of these cells. Thus, lin-44 mutants appear to generate polar cells but to misorient these cells along the body axis of the animal. We postulate that...
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