Article
The Caenorhabditis elegans gene lin-17, which is required for certain asymmetric cell divisions, encodes a putative seven-transmembrane protein similar to the Drosophila frizzled protein.
Genes & development - 1 Sept 1996
Sawa H, Lobel L, Horvitz H R
Abstract excerpt
Mutations in the gene lin-17 result in the disruption of a variety of asymmetric cell divisions in Caenorhabditis elegans. We have found that lin-17 encodes a protein with seven putative transmembrane domains. The LIN-17 protein is most similar to the Drosophila Frizzled protein and its vertebrat...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Blotting, Southern
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- Cell Division
- Cloning, Molecular
- Drosophila Proteins
- Frizzled Receptors
- Gene Expression Regulation, Developmental
- Genetic Variation
- Glycoproteins
- Helminth Proteins