Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Wnt signals and frizzled activity orient anterior-posterior axon outgrowth in C. elegans.

Developmental cell - 1 Mar 2006

Hilliard Massimo A, Bargmann Cornelia I

Abstract excerpt

Secreted proteins of the Wnt family affect axon guidance, asymmetric cell division, and cell fate. We show here that C. elegans Wnts acting through Frizzled receptors can shape axon and dendrite trajectories by reversing the anterior-posterior polarity of neurons. In lin-44/Wnt and lin-17/Frizzled mutants, the polarity of the PLM mechanosensory neuron is reversed along the body axis: the long PLM process, PLM...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Axons
Share to Body Patterning
Share to Caenorhabditis elegans Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cell Polarity

Share to Frizzled Receptors

Share to Glycoproteins

Share to Receptors, G-Protein-Coupled

Share to Wnt Proteins

Source

Identifiers

PMID: 16516840
DOI: 10.1016/j.devcel.2006.01.013

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Wnt signals and frizzled activity orient anterior-posterior axon outgrowth in C. elegans.PMID 16516840Read ↗

Wnt signaling establishes anteroposterior neuronal polarity and requires retromer in C. elegans.Semantic proximity Read ↗

Two Wnts instruct topographic synaptic innervation in C. elegans.Semantic proximity Read ↗

LIN-44/Wnt directs dendrite outgrowth through LIN-17/Frizzled in C. elegans Neurons.Semantic proximity Read ↗

A beta-catenin-dependent Wnt pathway mediates anteroposterior axon guidance in C. elegans motor neurons.Semantic proximity Read ↗

Distinct functions of three Wnt proteins control mirror-symmetric organogenesis in the C. elegans gonad.Semantic proximity Read ↗

Differential functions of multiple Wnts and receptors in cell polarity regulation in Caenorhabditis elegans.Semantic proximity Read ↗

FGF signaling regulates Wnt ligand expression to control vulval cell lineage polarity in C. elegans.Semantic proximity Read ↗

The C. elegans Frizzled CFZ-2 is required for cell migration and interacts with multiple Wnt signaling pathways.Semantic proximity Read ↗

Multiple levels of regulation specify the polarity of an asymmetric cell division in C. elegans.Semantic proximity Read ↗

Neurons refine the Caenorhabditis elegans body plan by directing axial patterning by Wnts.Semantic proximity Read ↗

The C. elegans gene lin-44, which controls the polarity of certain asymmetric cell divisions, encodes a Wnt protein and acts cell nonautonomously.Semantic proximity Read ↗

lin-17/Frizzled and lin-18 regulate POP-1/TCF-1 localization and cell type specification during C. elegans vulval development.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.