Article
Association study of bipolar disorder using a functional polymorphism (Ser311-->Cys) in the dopamine D2 receptor gene.
Psychiatric genetics - 1 Jan 1995
Craddock N, Roberts Q, Williams N, McGuffin P, Owen M J
Abstract excerpt
Several pieces of evidence are consistent with the involvement of dopamine neurotransmission in the aetiology of bipolar disorder. We have tested the hypothesis that the functional mutation Ser311-->Cys of the dopamine D2 receptor gene confers susceptibility to bipolar disorder. There was no incr...
Topics
- Alleles
- Bipolar Disorder
- Codon
- DNA Mutational Analysis
- Genes
- Genetic Predisposition to Disease
- Humans
- Point Mutation
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Psychotic Disorders
- Receptors, Dopamine D2
- Schizophrenia
- United Kingdom
- White People