Article
Association of dopamine D2 receptor molecular variant with schizophrenia.
Lancet (London, England) - 19 Mar 1994
Arinami T, Itokawa M, Enguchi H, Tagaya H, Yano S, Shimizu H, Hamaguchi H, Toru M
Abstract excerpt
We have examined a variant of the dopamine D2 receptor gene (Ser311-->Cys) in 156 Japanese schizophrenic patients and 300 controls. The allele frequency of Cys311 was significantly higher in the whole patient group (0.054), among patients with onset before age 25 (0.090), and among those with a family history (0.135) than in the controls (0.018). 3 patients were homozygous for Cys311. The patients with Cys311...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.