Article
Association of dopamine D2 receptor molecular variant with schizophrenia.
Lancet (London, England) - 19 Mar 1994
Arinami T, Itokawa M, Enguchi H, Tagaya H, Yano S, Shimizu H, Hamaguchi H, Toru M
Abstract excerpt
We have examined a variant of the dopamine D2 receptor gene (Ser311-->Cys) in 156 Japanese schizophrenic patients and 300 controls. The allele frequency of Cys311 was significantly higher in the whole patient group (0.054), among patients with onset before age 25 (0.090), and among those with a f...
Topics
- Adolescent
- Adult
- Aged
- Alleles
- Base Sequence
- Case-Control Studies
- Female
- Heterozygote
- Humans
- Japan
- Male
- Middle Aged
- Molecular Sequence Data