Article
No major role for the dopamine D2 receptor Ser-->Cys311 mutation in schizophrenia.
Psychiatric genetics - 1 Jan 1994
Laurent C, Bodeau-Péan S, Campion D, d'Amato T, Jay M, Dollfus S, Thibault F, Petit M, Samolyk D, Martinez M
Abstract excerpt
A new structural polymorphism (Ser311/Cys311) in the dopamine D2 receptor (DRD2) gene has recently been reported to be associated with schizophrenia, particularly in patients with a positive family history of schizophrenia (Arinimi et al., 1994). However these findings remain controversial (Asherson et al., 1994; Nanko et al., 1994; Nöthen et al., 1994; Shaikh et al., 1994). Thus we investigated the role of the...
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