No major role for the dopamine D2 receptor Ser-->Cys311 mutation in schizophrenia.

doi:10.1097/00041444-199400440-00007

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Article

No major role for the dopamine D2 receptor Ser-->Cys311 mutation in schizophrenia.

Psychiatric genetics - 1 Jan 1994

Laurent C, Bodeau-Péan S, Campion D, d'Amato T, Jay M, Dollfus S, Thibault F, Petit M, Samolyk D, Martinez M

Abstract excerpt

A new structural polymorphism (Ser311/Cys311) in the dopamine D2 receptor (DRD2) gene has recently been reported to be associated with schizophrenia, particularly in patients with a positive family history of schizophrenia (Arinimi et al., 1994). However these findings remain controversial (Asher...

Topics

Alleles
Cysteine
Female
France
Gene Frequency
Humans
Male
Pedigree
Point Mutation
Receptors, Dopamine D2
Schizophrenia
Serine
White People

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