Article
No evidence for association of dopamine D2 receptor variant (Ser311/Cys311) with major psychosis.
American journal of medical genetics - 26 Jul 1996
Sasaki T, Macciardi F M, Badri F, Verga M, Meltzer H Y, Lieberman J, Howard A, Bean G, Joffe R T, Hudson C J, Kennedy J L
Abstract excerpt
We investigated a variant of the dopamine D2 receptor gene (Ser311/Cys311 substitution) in Caucasian patients with schizophrenia (n = 273), delusional disorder (n = 62), bipolar I affective disorder (n = 63), and controls (n = 255). No evidence for association between the receptor variant and any of the diseases was found, even when patients with younger age-of-onset (< 25 years) were compared with controls....
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