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Article

No evidence for association of dopamine D2 receptor variant (Ser311/Cys311) with major psychosis.

American journal of medical genetics - 26 Jul 1996

Sasaki T, Macciardi F M, Badri F, Verga M, Meltzer H Y, Lieberman J, Howard A, Bean G, Joffe R T, Hudson C J, Kennedy J L

Abstract excerpt

We investigated a variant of the dopamine D2 receptor gene (Ser311/Cys311 substitution) in Caucasian patients with schizophrenia (n = 273), delusional disorder (n = 62), bipolar I affective disorder (n = 63), and controls (n = 255). No evidence for association between the receptor variant and any...

Topics

Adult
Age of Onset
Amino Acid Sequence
Bipolar Disorder
Cysteine
Delusions
Female
Genetic Variation
Humans
Male
Middle Aged
Psychotic Disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Receptors, Dopamine D2

Reference Values

Schizophrenia

Serine

White People

Source

Identifiers

PMID: 8837713
DOI: 10.1002/(SICI)1096-8628(19960726)67:4<415::AID-AJMG18>3.0.CO;2-M

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8837713-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Related research

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No evidence for association of dopamine D2 receptor variant (Ser311/Cys311) with major psychosis.PMID 8837713Read ↗

Dopamine DRD2/Cys311 is not associated with chronic schizophrenia.Semantic proximity Read ↗

No major role for the dopamine D2 receptor Ser-->Cys311 mutation in schizophrenia.Semantic proximity Read ↗

No association of dopamine D2 receptor molecular variant Cys311 and schizophrenia in Chinese patients.Semantic proximity Read ↗

Dopamine receptor D2 Ser/Cys 311 variant is associated with delusion and disorganization symptomatology in major psychoses.Semantic proximity Read ↗

Association of dopamine D2 receptor molecular variant with schizophrenia.Semantic proximity Read ↗

Dopamine D2 receptor gene Ser311Cys variant and schizophrenia: association study and meta‐analysisSemantic proximity Read ↗

Lack of association between dopamine D2 receptor gene Cys311 variant and schizophrenia.Semantic proximity Read ↗

Further association study on dopamine D2 receptor variant S311C in schizophrenia and affective disorders.Semantic proximity Read ↗

European Multicentre Association Study of Schizophrenia: a study of the DRD2 Ser311Cys and DRD3 Ser9Gly polymorphisms.Semantic proximity Read ↗

Association of DRD2 gene variant with schizophrenia.Semantic proximity Read ↗

No association of the Ser/Cys311 DRD2 molecular variant with schizophrenia using a classical case control study and the haplotype relative risk.Semantic proximity Read ↗

Association study of bipolar disorder using a functional polymorphism (Ser311-->Cys) in the dopamine D2 receptor gene.Semantic proximity Read ↗

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