Dopamine D2 receptor gene Ser311Cys variant and schizophrenia: association study and meta‐analysis

doi:10.1002/ajmg.b.20004

Article

Dopamine D2 receptor gene Ser311Cys variant and schizophrenia: association study and meta‐analysis

22 Jan 2003

Abstract excerpt

An association has been reported between a dopamine D(2) receptor gene (DRD2) Ser311Cys variant and schizophrenia. In a replication attempt, Swedish patients with schizophrenia (n = 173) and control subjects (n = 236) were assessed for the DRD2 Ser311Cys variant. Schizophrenic patients displayed higher Cys311 allele frequencies than control subjects (4.0 vs. 0.8%, chi(2) = 9.49, df = 1, P = 0.002; odds ratio (OR)...

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.