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Article

Dopamine DRD2/Cys311 is not associated with chronic schizophrenia.

American journal of medical genetics - 20 Sept 1996

Crawford F, Hoyne J, Cai X, Osborne A, Poston D, Zaglul J, Dajani N, Walsh S, Bradley R, Solomon R, Mullan M

Abstract excerpt

A mutation in the DRD2 receptor gene has been reported in association with schizophrenia in Japanese and Caucasian populations. The variation, Ser to Cys at codon 311, occurs in the third intracellular loop of the receptor and is therefore putatively functional. We report the results of screening US Caucasian schizophrenic and nonschizophrenic populations. We detected the occurrence of the DRD2 Cys311 variant in...

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Source

Identifiers

PMID: 8886166
DOI: 10.1002/(SICI)1096-8628(19960920)67:5<483::AID-AJMG8>3.0.CO;2-L

Genes

DRD2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dopamine DRD2/Cys311 is not associated with chronic schizophrenia.PMID 8886166Read ↗

No association of dopamine D2 receptor molecular variant Cys311 and schizophrenia in Chinese patients.Semantic proximity Read ↗

No major role for the dopamine D2 receptor Ser-->Cys311 mutation in schizophrenia.Semantic proximity Read ↗

No evidence for association of dopamine D2 receptor variant (Ser311/Cys311) with major psychosis.Semantic proximity Read ↗

Association of dopamine D2 receptor molecular variant with schizophrenia.Semantic proximity Read ↗

Dopamine D2 receptor gene Ser311Cys variant and schizophrenia: association study and meta‐analysisSemantic proximity Read ↗

Lack of association between dopamine D2 receptor gene Cys311 variant and schizophrenia.Semantic proximity Read ↗

The Cys allele of the DRD2 Ser311Cys polymorphism has a dominant effect on risk for schizophrenia: evidence from fixed- and random-effects meta-analyses.Semantic proximity Read ↗

A structural polymorphism of human dopamine D2 receptor, D2(Ser311-->Cys).Semantic proximity Read ↗

Advanced research on dopamine signaling to develop drugs for the treatment of mental disorders: Ser311Cys polymorphisms of the dopamine D2-receptor gene and schizophrenia.Semantic proximity Read ↗

European Multicentre Association Study of Schizophrenia: a study of the DRD2 Ser311Cys and DRD3 Ser9Gly polymorphisms.Semantic proximity Read ↗

Association of DRD2 gene variant with schizophrenia.Semantic proximity Read ↗

An association study between the Cys311 variant of dopamine D2 receptor gene and schizophrenia in the Okinawan population.Semantic proximity Read ↗

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