Article
Dopamine DRD2/Cys311 is not associated with chronic schizophrenia.
American journal of medical genetics - 20 Sept 1996
Crawford F, Hoyne J, Cai X, Osborne A, Poston D, Zaglul J, Dajani N, Walsh S, Bradley R, Solomon R, Mullan M
Abstract excerpt
A mutation in the DRD2 receptor gene has been reported in association with schizophrenia in Japanese and Caucasian populations. The variation, Ser to Cys at codon 311, occurs in the third intracellular loop of the receptor and is therefore putatively functional. We report the results of screening...
Topics
- Asian People
- Base Sequence
- Codon
- Cysteine
- DNA Primers
- Gene Frequency
- Genetic Variation
- Humans
- Japan
- Point Mutation
- Polymerase Chain Reaction
- Receptors, Dopamine D2
- Schizophrenia
- Serine
- United States
- White People