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Article

Characterization of the N-terminal half-saturated state of calbindin D9k: NMR studies of the N56A mutant.

Protein science : a publication of the Protein Society - 1 Jun 1995

Wimberly B, Thulin E, Chazin W J

Abstract excerpt

Calbindin D9k is a small EF-hand protein that binds two calcium ions with positive cooperativity. The molecular basis of cooperativity for the binding pathway where the first ion binds in the N-terminal site (1) is investigated by NMR experiments on the half-saturated state of the N56A mutant, which exhibits sequential yet cooperative binding (Linse S, Chazin WJ, 1995, Protein Sci 4:1038-1044). Analysis of...

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Identifiers

PMID: 7549869
DOI: 10.1002/pro.5560040603
PMCID: PMC2143144

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Characterization of the N-terminal half-saturated state of calbindin D9k: NMR studies of the N56A mutant.PMID 7549869Read ↗

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