The first intracellular loop of GLUT4 contains a retention motif.

Abstract excerpt

Glucose transporter GLUT4 (also known as SLC2A4) plays a major role in glucose homeostasis and is efficiently retained intracellularly in adipocytes and myocytes. To simplify the analysis of its retention, here, various intracellular GLUT4 domains were fused individually to reporter molecules. Of the four short cytoplasmic loops of GLUT4, only the first nine-residue-long loop conferred intracellular retention of...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to 3T3-L1 Cells
• Share to Adipocytes
• Share to CD4 Antigens