Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An intracellular motif of GLUT4 regulates fusion of GLUT4-containing vesicles.

BMC cell biology - 20 May 2008

Heyward Catherine A, Pettitt Trevor R, Leney Sophie E, Welsh Gavin I, Tavaré Jeremy M, Wakelam Michael J O

Abstract excerpt

BACKGROUND: Insulin stimulates glucose uptake by adipocytes through increasing translocation of the glucose transporter GLUT4 from an intracellular compartment to the plasma membrane. Fusion of GLUT4-containing vesicles at the cell surface is thought to involve phospholipase D activity, generating the signalling lipid phosphatidic acid, although the mechanism of action is not yet clear. RESULTS: Here we report...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3T3-L1 Cells
Share to Adipocytes
Share to Biological Transport, Active

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cytoplasmic Vesicles

Share to Glucose Transporter Type 4

Share to Membrane Fusion

Share to Mutant Proteins

Share to Peptide Library

Source

Open in PubMed Open full text

Identifiers

PMID: 18492238
DOI: 10.1186/1471-2121-9-25
PMCID: PMC2405794

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An intracellular motif of GLUT4 regulates fusion of GLUT4-containing vesicles.PMID 18492238Read ↗

Molecular regulation of GLUT-4 targeting in 3T3-L1 adipocytes.Semantic proximity Read ↗

Protein kinase B phosphorylation of PIKfyve regulates the trafficking of GLUT4 vesicles.Semantic proximity Read ↗

GLUT4 is sorted to vesicles whose accumulation beneath and insertion into the plasma membrane are differentially regulated by insulin and selectively affected by insulin resistance.Semantic proximity Read ↗

Direct demonstration of insulin-induced GLUT4 translocation to the surface of intact cells by insertion of a c-myc epitope into an exofacial GLUT4 domainSemantic proximity Read ↗

The first intracellular loop of GLUT4 contains a retention motif.Semantic proximity Read ↗

Insulin-stimulated phosphorylation of a Rab GTPase-activating protein regulates GLUT4 translocation.Semantic proximity Read ↗

Similar [DE]XXXL[LI] motifs differentially target GLUT8 and GLUT12 in Chinese hamster ovary cells.Semantic proximity Read ↗

A Protein Kinase C Phosphorylation Motif in GLUT1 Affects Glucose Transport and is Mutated in GLUT1 Deficiency SyndromeSemantic proximity Read ↗

Calmodulin binds to the Rab GTPase activating protein required for insulin-stimulated GLUT4 translocation.Semantic proximity Read ↗

EHD2 interacts with the insulin-responsive glucose transporter (GLUT4) in rat adipocytes and may participate in insulin-induced GLUT4 recruitment.Semantic proximity Read ↗

Identification and characterization of p49/STRAP as a novel GLUT4-binding protein.Semantic proximity Read ↗

Deciphering the role of GLUT4 N-glycosylation in adipocyte and muscle cell models.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.